ABOUT US
Epigen is discovering novel therapies for unmet medical needs
Epigen is a start-up pharmaceutical company with a mission to discover innovative, proprietary drugs for unmet medical needs. The company works in a highly collaborative translational manner, to facilitate the transition of discoveries from laboratory to clinic. We operate through collaboration with academic groups in their respective areas of expertise. Epigen provides strategic project management and medicinal chemistry support. The company founders have over 50 years combined successful experience in drug discovery and development and a track record of advancing compounds to the clinic and commercial registration. The company creates value by bridging the gap between lead identification and clinical proof-of concept. Ideally, each asset will have a 2-5 years turnaround time from IP to IND enablement and completion of Phase 1 studies. Epigen uses advanced hit-to-lead and lead optimization methods, such as computational design, scaffold-hopping, focused library synthesis and screening. We use modern in silico drug discovery tools in concert with ADME property determination. Our established network of resources gives us the capability to discover assets and advance them beyond IND stage into early clinical trials through the evaluation of physicochemical properties, solubility, metabolic stability, CYP450 inhibition, hERG liability, oral bioavailability, CNS penetration, toxicology and in vivo efficacy.
OPEN POSITIONS
We’re hiring, please apply at
RESEARCH SCIENTIST - CHEMISTRY
The position offers significant growth opportunities in terms of contributing to the development of science and individual growth
Requires a Ph.D. in synthetic organic chemistry or related field, 1+ years industry/postdoctoral experience
May supervise junior level chemist
Experience with modern synthetic organic chemistry, purification, and analysis is required
Experience with using ChemDraw/Reaxys/SciFinder
Performance of routine synthesis of heterocyclic compounds in milligram to multi-gram scale to support lead identification and optimization and record-keeping
Performance of purification of synthesized compounds using prep-TLC, silica gel/C18 column chromatography
Performance of and analyzing compounds using NMR spectra and LCMS
Performance of Microsoft Office tools such as Word, Excel, PowerPoint and Outlook
Good communication and presentation skills to effectively work with cross-functional groups with diverse background and interests
Strong attention to detail, excellent written and oral communication skills
Ability to work with a team of individuals to meet goals
Must be physically capable of lifting 50 pounds
SENIOR RESEARCH ASSOCIATE/RESEARCH ASSOCIATE - CHEMISTRY
The position offers significant growth opportunities in terms of contributing to the development of science and individual growth
Requires an MS/BS in synthetic organic chemistry or related field, 1+ years industry experience
Experience with modern synthetic organic chemistry, purification, and analysis is required
Experience with using ChemDraw/Reaxys/SciFinder
Performance of routine synthesis of heterocyclic compounds in milligram to multi-gram scale to support lead identification and optimization and record-keeping
Performance of purification of synthesized compounds using prep-TLC, silica gel/C18 column chromatography
Performance of and analyzing compounds using NMR spectra and LCMS
Performance of Microsoft Office tools such as Word, Excel, PowerPoint and Outlook
Good communication and presentation skills to effectively work with cross-functional groups with diverse background and interests
Strong attention to detail, excellent written and oral communication skills
Ability to work with a team of individuals to meet goals
Must be physically capable of lifting 50 pounds
RESEARCH SCIENTIST - BIOLOGY
Position offers significant growth opportunities in terms of contributing to the development of science and individual growth.
Requires a PhD in biology or related field, 1+ years industry/postdoctoral experience.
May supervise junior level biologist
Experience with cell culture and cell-based in vitro assays is required
Experience with the development and optimization of in vitro biological assays is required
Performance of routine assays to support lead identification and optimization
Performance of molecular biology techniques, such as Western blotting and transient transfection
Performance of data analysis, reporting and record keeping
Performance of Microsoft Office tools such as Word, Excel, PowerPoint and Outlook
Good communication and presentation skills to effectively work with cross-functional groups with diverse background and interests
Strong attention to detail, excellent written and oral communication skills
Ability to work with a team of individuals to meet goals
Must be physically capable of lifting 50 pounds
SENIOR RESEARCH ASSOCIATE/RESEARCH ASSOCIATE - BIOLOGY
Position offers significant growth opportunities in terms of contributing to the development of science and individual growth
Requires an MS/BS in biology or related field, 1+ years industry experience
Experience with cell culture and cell-based in vitro assays is required
Experience with the development and optimization of in vitro biological assays is required
Performance of routine assays to support lead identification and optimization
Performance of molecular biology techniques, such as Western blotting and transient transfection
Performance of data analysis, reporting and record keeping
Performance of Microsoft Office tools such as Word, Excel, PowerPoint and Outlook
Good communication and presentation skills to effectively work with cross-functional groups with diverse background and interests
Strong attention to detail, excellent written and oral communication skills
Ability to work with a team of individuals to meet goals
Must be physically capable of lifting 50 pounds